Using genome sequencing, researchers at the University of Hong Kong have found a rare instance of reinfection with novel coronavirus for the second time, four-and-a-half months after the first infection. The first viral genome belongs to GISAID clade V, while the second genome belongs to GISAID clade G. Using genome sequencing, researchers at the UniversityContinue reading “A case of coronavirus reinfection in Hong Kong confirmed by genome sequencing”
Author Archives: CS
Children have more coronavirus during early infection phase than hospitalised adults
Researchers found that children infected with novel coronavirus have viral load comparable with adults admitted to ICUs. But during the early infection phase, children can have significantly higher viral load than COVID-19 adults in ICUs. Viral load decreases over time in children. Age of children did not have any impact on viral load. Researchers MassachusettsContinue reading “Children have more coronavirus during early infection phase than hospitalised adults”
Intranasal vaccination of a coronavirus candidate vaccine prevents infection
A new vaccine candidate construct using chimpanzee adenovirus carrying the full length of novel coronavirus spike protein is able to achieve sterilizing immunity and prevent both upper and lower respiratory tract infection in mice when administered intranasally but not when given via the intramuscular route. A new vaccine candidate construct using chimpanzee adenovirus carrying […] ToContinue reading “Intranasal vaccination of a coronavirus candidate vaccine prevents infection”
COVID-19: Saliva is a viable alternative to nasopharyngeal specimen in asymptomatic persons
In a mass-screening study of 1,924 asymptomatic persons, self-collected saliva samples had sensitivity (92%) and specificity (over 99.9%) comparable to nasopharyngeal specimens — sensitivity 86% and specificity over 99.9%. The true concordance probability between the nasopharyngeal and saliva tests was estimated at 0.998. In a mass-screening study of 1,924 asymptomatic persons using nasopharyngeal and self-collectedContinue reading “COVID-19: Saliva is a viable alternative to nasopharyngeal specimen in asymptomatic persons”
FDA approves rapid, inexpensive saliva test for coronavirus
A rapid, inexpensive saliva test developed by Yale School of Public Health in partnership with NBA has high sensitivity. The testing protocol has been made available through “open source”. The SalivaDirect test does not use any preservative at time of collection, uses commonly available reagents, and does not need equipment for nucleic acid extraction. InContinue reading “FDA approves rapid, inexpensive saliva test for coronavirus”
Buffers and Guidelines on the use of buffers in HPLC Methods
Buffers and Guidelines on the use of buffers in HPLC Methods
A buffer solution is a solution that resists changes to a solution’s pH, when small quantities of acid or alkali are added to the solution. Use of buffer plays an important role in HPLC separation, change can separate two closely eluting peaks and may merge two separate peaks. The most commonly used buffers in LC are citrate, acetate and phosphate buffer.Continue reading “Buffers and Guidelines on the use of buffers in HPLC Methods”
Total Quality Management in Pharmaceutical Industry
Introduction: Total Quality Management is a systematic approach for the continual improvement of all Organization processes, through the participation of all the staff, leading to prime quality product and services to achieve customer satisfaction It is supported by the philosophy: “Do the right things, right first time, every time”. Principles of Total Quality Management: TheContinue reading “Total Quality Management in Pharmaceutical Industry”
Quality Management System in Pharmaceuticals
A Quality Management System (QMS) is defined as a system that documents processes, procedures, and responsibilities for achieving quality policies and objectives. QMS is the core of the quality and compliance process for any organization. It helps in the reduction of audit time and findings, it also helps in product recalls. A QMS helps coordinateContinue reading “Quality Management System in Pharmaceuticals”
Introduce Yourself (Example Post)
This is an example post, originally published as part of Blogging University. Enroll in one of our ten programs, and start your blog right. You’re going to publish a post today. Don’t worry about how your blog looks. Don’t worry if you haven’t given it a name yet, or you’re feeling overwhelmed. Just click theContinue reading “Introduce Yourself (Example Post)”