IGIB uses mass spectrometer for coronavirus detection — Science Chronicle

IGIB researchers have been able to detect novel coronavirus using mass spectrometer. The detection is based on the presence of two unique peptides of the virus. Sensitivity is 95% and specificity is 100% and takes less than 30 minutes from sample preparation to testing. Using mass spectrometer, researchers at the Delhi-based Institute of Genomics and […]Continue reading “IGIB uses mass spectrometer for coronavirus detection — Science Chronicle”

Early detection of cancer using a blood test

Blood test is one of the simplest, yet most informative weapons in your doctor’s arsenal. A tiny needle prick and a few millilitres of blood can help doctors 1) evaluate how your body’s vital organs like heart, liver, kidneys and thyroid are functioning, 2) diagnose diseases such as diabetes, cancer, heart disease and communicable diseases […]Continue reading “Early detection of cancer using a blood test”

A case of coronavirus reinfection in Hong Kong confirmed by genome sequencing

Using genome sequencing, researchers at the University of Hong Kong have found a rare instance of reinfection with novel coronavirus for the second time, four-and-a-half months after the first infection. The first viral genome belongs to GISAID clade V, while the second genome belongs to GISAID clade G. Using genome sequencing, researchers at the UniversityContinue reading “A case of coronavirus reinfection in Hong Kong confirmed by genome sequencing”

Children have more coronavirus during early infection phase than hospitalised adults

Researchers found that children infected with novel coronavirus have viral load comparable with adults admitted to ICUs. But during the early infection phase, children can have significantly higher viral load than COVID-19 adults in ICUs. Viral load decreases over time in children. Age of children did not have any impact on viral load. Researchers MassachusettsContinue reading “Children have more coronavirus during early infection phase than hospitalised adults”

Intranasal vaccination of a coronavirus candidate vaccine prevents infection

A new vaccine candidate construct using chimpanzee adenovirus carrying the full length of novel coronavirus spike protein is able to achieve sterilizing immunity and prevent both upper and lower respiratory tract infection in mice when administered intranasally but not when given via the intramuscular route. A new vaccine candidate construct using chimpanzee adenovirus carrying […] ToContinue reading “Intranasal vaccination of a coronavirus candidate vaccine prevents infection”

COVID-19: Saliva is a viable alternative to nasopharyngeal specimen in asymptomatic persons

In a mass-screening study of 1,924 asymptomatic persons, self-collected saliva samples had sensitivity (92%) and specificity (over 99.9%) comparable to nasopharyngeal specimens — sensitivity 86% and specificity over 99.9%. The true concordance probability between the nasopharyngeal and saliva tests was estimated at 0.998. In a mass-screening study of 1,924 asymptomatic persons using nasopharyngeal and self-collectedContinue reading “COVID-19: Saliva is a viable alternative to nasopharyngeal specimen in asymptomatic persons”

FDA approves rapid, inexpensive saliva test for coronavirus

A rapid, inexpensive saliva test developed by Yale School of Public Health in partnership with NBA has high sensitivity. The testing protocol has been made available through “open source”. The SalivaDirect test does not use any preservative at time of collection, uses commonly available reagents, and does not need equipment for nucleic acid extraction. InContinue reading “FDA approves rapid, inexpensive saliva test for coronavirus”